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Femara (Letrozole)

Femara (Letrozole)

Pack of 30 tablets. 2.5mg of Letrozole per tab. Letrodex is a non steroidal anti-aromatase compound used to lower estrogens in the body.

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Femara (Letrozole)
Rating: 4 based on 34 reviews

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Pack of 30 tablets. 2.5mg of Letrozole per tab. Letozole is a non steroidal anti-aromatase compound used to lower estrogens in the body.

What does Letrozole do?

Letrozole is an oral non-steroidal aromatase inhibitor prescribed for the treatment of local or metastatic breast cancer - either hormone receptor positive, or with an unknown receptor status, in postmenopausal women.

Letrozole is used to treat early breast cancer in postmenopausal women who have received 5 years of adjuvant tamoxifen therapy; also to treat advanced breast cancer in women with disease progression after anti-estrogen therapy. It can also be used to treat infertility due to the polycystic ovary syndrome (PCOS).

Letrozole is known to delay the fusing of the growth plates in adolescents (what is likely to boost the effectiveness of growth hormone) therefore, letrozole can also be used to treat children with short stature.


How does Letrozole work?

Letrozole reversibly inhibits the aromatase enzyme, which normally converts androgens (like testosterone) to estrogens. Letrozole binds the heme on P450 unit of the aromatase enzyme making it unable to carry out its usual functions this way blocking production of the estrogens. This binding action is specific: letrozole selectively inhibits gonadal steroidogenesis but has no significant effect on adrenal mineralocorticoid or glucocorticoid synthesis.

Since breast tissue is stimulated by estrogens, decreasing their production suppresses recurrence of the breast tumour tissue. In adult tumour-bearing females, letrozole is as effective as ovariectomy in reducing uterine weight, increasing serum LH, and causing the regression of estrogen-dependent tumours. Unlike ovariectomy, letrozole does not increase serum FSH levels.

Before taking letrozole:

Doctor’s instructions should be followed at all times. Letrozole should be not taken:

  • with allergy to letrozole or any inactive ingredient
  • by pre-menopausal women
  • during pregnancy
  • while breast-feeding
  •  by children and adolescents

Doctor or pharmacist should be consulted if the patient has a severe kidney or liver disease, has a history of osteoporosis or bone fractures

How to use femara for gynecomastia:

Day 1: 0.50mg Letrozole
Day 2: 1.0mg Letrozole
Day 3: 1.5mg Letrozole
Day 4: 2.0mg Letrozole
Day 5: 2.5mg Letrozole

Use until gyno subsides then:

Day 1: 2.0mg Letrozole
Day 2: 1.5mg Letrozole
Day 3: 1.0mg Letrozole
Day 4: 0.50mg Letrozole
Day 5: 0.25mg Letrozole

Very important: Then take 20mg Tamoxifen (Nolvadex) per day for 2 weeks

How to use femara for PCOS or female infertility:

Take 2.5mg of letrozole from day 2 to day 7 of period week only. Femara is only used 5 days per month for this purpose.


Safety Information and Side Effects

Side effects are usually mild and include signs of hypoestrogenism: headache, joint pain, fatigue, hair thinning, in women: vaginal dryness and vaginal bleeding. The mmost common side effects include hot flushes, increased level of cholesterol (hypercholesterolaemia), fatigue, increased sweating, and pain in bones and joints (arthralgia). Long term use may lead to osteoporosis, thus treatment with letrozole can be combined with anti-osteoporosis medication.

Letrozole can reduce estrogen levels by 98 percent while increasing testosterone levels at the same time. This can be utilised for use during steroid cycles: to reduce bloating due to excess water retention and to prevent formation of gynecomastia (side effect of some anabolic steroids). Daily dose above 2.5mg is known to potentially temporarily kill sex drive. Use of doses over 5mg per day for extended periods may cause kidney problems.



As always totally legit tablets always happy & thankful for this site!!♡



I have purchased this product twice now and both times I have been very happy with the results. very good stuff! I take 1/4 of a tablet each day while on cycle and for 3 weeks afterwards and it does a great job. lump size drastically reduced, not sore and no itchy feeling. would recommend



Received within 3days of cleared payment.
Currently using and lumps have decreased. So far so good



Left a review only to have it deleted. Nice. Guess they want fake reviews. This stuff didn't work for me. I'm not saying it's crap- it just didn't do anything for me at all. I feel like I wasted my money. If you're TTC like I am, it's worth a shot of course, but just don't be too disappointed when it doesn't work. Maybe they'll keep my review now that I rated 3 stars instead of 1 like it needs to be.



looks legit i see differences after few day of used. definitely will use this site again!!



Livraison rapide et discrète, très bon produit.



Great product great customer service highly recommend



Does exactly what its supposed to do!!
Got rid of painfull lumps within days!
Would highly recommend.
I was having second thoughts about this site at first,because of some negative feedback,but i had to see for myself.
The product and customer service is second to none!!!
Had my delivery in 2 days!
Any questions to customer service ,answered promptly.
I would give this site 10 stars!!



I thought these reviews were all fake, but they aren't. Gyno in my left breast is gone... and is reducing on the right side.. didn't work as fast as i'd hoped... but worked nonetheless.

PS. Be prepared to have NO sex drive! Literally none!



this is my second purchase of letrozole has a painfull lump in right peck. tried tamoxifen and arimadex but nothing worked..this got rid of it in a week its strong stuff..only downside was my sexdrive vanished this time round with my course im just gonna take 0.75 every other day to keep gyno in check..was a bit sceptical first time ordering but the product and service was amazing..:)

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